Chargers vs. Chiefs prediction, odds, spread, injuries, trends for NFL Week 7

Breaking down the betting odds, trends, and best bet for NFL Week 7 action between the Chargers and Chiefs.
Sep 15, 2022; Kansas City, Missouri, USA; Los Angeles Chargers quarterback Justin Herbert (10)
Sep 15, 2022; Kansas City, Missouri, USA; Los Angeles Chargers quarterback Justin Herbert (10) / Denny Medley-USA TODAY Sports

The Los Angeles Chargers suffered a heart breaking loss on Monday Night Football in Week 6, and are now just 2-3 on the season.

The bad news is they now have to head to Kansas City to take on the Chiefs, the good news is a win here would be absolutely massive and get them back into the thick of things.

If you want my picks for every Week 7 game, check out the latest edition of the "Road to 272 Bets" here!

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Chargers vs. Chiefs odds, spread, and total

Chargers vs. Chiefs betting trends

  • Chargers are 2-4 ATS in their last six games
  • Chargers are 5-1 ATS in their last six games vs. Chiefs
  • Chargers are 3-15 straight up in their last 18 games vs. Chiefs
  • Chargers are 8-4 ATS in their last 12 road games
  • Chiefs are 4-1 ATS in their last five games
  • The UNDER 7-3 in their last 10 games
  • Chiefs are 9-0 straight up in their last nine games vs. AFC opponents

Chargers vs. Chiefs injury reports

Los Angeles Chargers injury report

  • Alohi Gilman - S - Questionable
  • Deane Leonard - CB - Questionable
  • Raheem Layne - S - Questionable

Kansas City Chiefs injury report

  • The Chiefs currently have no players on their active injury report

Chargers vs. Chiefs how to watch

  • Date: Sunday, Oct. 22
  • Game Time: 4:25 p.m. EST
  • Venue: GEHA Field at Arrowhead Stadium
  • How to Watch (TV): CBS
  • Los Angeles Chargers Record: 2-3
  • Kansas City Chiefs Record: 5-1

Chargers vs. Chiefs key players to watch

Los Angeles Chargers

Justin Herbert: After Monday night's loss, people are starting to question Justin Herbert. He's still a great quarterback, but is he the elite player we all thought he was? He has a big chance to silence the critics and beat their divisional rival in Week 7. As is usually the case, he's the guy to watch on Sunday.

Kansas City Chiefs

Rashee Rice: The Chiefs have been desperate to find out who their No. 1 guy at wideout is, and Rashee Rice has started to establish himself as that guy. His snap count as increased each week and he continues to deliver in every game. He's the key to the Chiefs attacking this Chargers secondary.

Chargers vs. Chiefs prediction and pick

Every week, I pick one team to pull off the upset as underdogs. This week, that team is the Los Angeles Chargers.

The Chiefs have been playing with fire the past few weeks, allowing far inferior opponents to stick around far too long in their games. They've come out with the win in each of those games, but that can't last forever.

The Chargers defense has made huge improvements in recent weeks, and while their offense didn't look great on Monday, they can hang with the Chiefs when they're firing on all cylinders.

It's time to buy low on the Chargers after their Week 6 loss. I think they win this game outright on Sunday.

Odds refresh periodically and are subject to change.

You can check out all of Iain's bets here!