1. Patrick Mahomes
I mean, duh.
Patrick Mahomes is the best player in the NFL and there is a reason why he received the most expensive contract in American sports history from the Kansas City Chiefs after just two seasons as a starting quarterback.
If Mahomes continues at his current pace, which we have no reason to expect him not to, then he is going to be the greatest quarterback of all-time, period. He has been a starter for two seasons and is already a Super Bowl Champion, an MVP and has a 5,000-yard, 50 touchdown season.
If it was not for Dee Ford being offsides in the 2019 AFC Championship Game then Mahomes would probably be a two-time Super Bowl Champion. He is a once in a generation talent and still has the best weapons in football around him.
The Chargers, however, have done a good job in slowing him down in their matchups. While they have not completely stopped Mahomes, they have limited his explosiveness and kept the Chiefs close.
That is, outside of the first matchup, where Mahomes took the Chargers and the NFL by storm. But a lot of that game was because of Tyreek Hill making plays happen.
Even if the Chargers have better success than other teams it is still undeniable that Mahomes is the toughest quarterback to match up against in all of football.